The Mayo clinical score for assessment of ulcerative colitis (UC) activity includes 4 items:
| Stool frequency (per day) | 0 = normal number of stool for patient
1 = 1-2 stools more than normal 2 = 3-4 stools more than normal 3 = 5+ stools more than normal |
| Rectal bleeding | 0 = no blood seen
1 = streaks of blood with stool less than half the time 2 = obvious blood with stool most of the time 3 = blood alone passes |
| Findings on endoscopy (Mayo endoscopic score) | 0 = normal or inactive disease
1 = mild disease (erythema, decreased vascular pattern, mild friability) 2 = moderate disease (marked erythema, absent vascular pattern, friability, erosions) 3 = severe disease (spontaneous bleeding, ulcerations) |
| Physician global assessment of disease activity | 0 = normal
1 = mild 2 = moderate 3 = severe |
Interpretation
| Scores | Disease severity |
| ≤ 2 and no subscore > 1 | clinical remission |
| 3-5 | mild activity |
| 6-10 | moderate activity |
| 11-12 | severe activity |
An online calculator is available at globalrph.com.
Reference: Rutgeerts P, Sandborn WJ, Feagan BG, et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med. 2005;353(23):2462-76.