Where to look for dysplasia and neoplasia in Barrett’s esophagus?

When assessing a patient with Barrett’s esophagus (BE), one should be aware that BE-associated dysplastic and neoplastic lesions are not equally distributed within the esophageal circumference.

There are several studies looking at the spatial distribution of early neoplastic lesions in BE patients reporting that most of these lesions usually occur between 12-15 o’clock.

This preferential location of dysplastic/neoplastic lesions should prompt the endoscopist for a careful examination of the area.

Moriyama N et al. Am J Gastro 2006


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